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AlphaGenome Atlas: a high-resolution map of human DNA
AlphaGenome Atlas is a 1-petabyte database that predicts the effects of all 9 billion single nucleotide variants in the human genome. It uses the AlphaGenome AI model to map how genetic mutations affect molecular biology.
Why it matters
This tool allows researchers to identify genetic causes of rare diseases and complex traits more quickly. It simplifies genomic data, helping scientists find critical mutations without needing coding skills.
The big picture
This article introduces the AlphaGenome Atlas, the tool previously linked to Gareth Hawkes and the Broad Institute in existing records.
The details
Laura Covill at the Broad Institute used the AVI score to identify a critical variant in the DNM1 gene. Dr. Gareth Hawkes used the Atlas with UK Biobank data to uncover 22% more non-coding genetic associations and identify 19 regions linked to body mass index.
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In this article
Key connections
AlphaGenome Atlas is built with AlphaGenome
We used the AlphaGenome AI model to pre-calculate the regulatory impact of all 9 billion single-letter genetic changes, resulting in a massive, 1-petabyte dataset.
Laura Covill works at Broad Institute
At the Broad Institute, Laura Covill and her team used the AVI score
Gareth Hawkes uses AlphaGenome Atlas
Dr. Gareth Hawkes applied AlphaGenome Atlas to data from 54,000+ UK Biobank participants
Gareth Hawkes is related to UK Biobank
Dr. Gareth Hawkes applied AlphaGenome Atlas to data from 54,000+ UK Biobank participants
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